The present study aimed at investigating and comparing the effects of telmisartan and valsartan on systolic blood pressure (SBP), diastolic blood pressure (DBP), serum leptin level, fasting serum glucose (FSG), fasting serum insulin, homeostasis model assessment of insulin resistance (HOMA-IR), BMI, waist circumference, serum uric acid level in type 2 diabetes mellitus (T2DM) patients with new diagnosis of hypertension, to achieve the aims of the present study, a randomized controled comparative trial with open label design was adopted from 1st of February, 2012 to 30th of march, 2013. The study's patients were confined to already diabetic type 2, but with new diagnosis of hypertension. Patients continued the follow up period were 88 subjects; 46 on telmisartan (80mg/day) and 42 enrolled with valsartan (80mg/day). Fourty one diabetic normotensive patients,II age, sex, body mass index (BMI), duration of diabetic disease, duration of diabetic treatment matched to the diabetic hypertensiv