This study follows the partial inductive approach to identify the Prophetic Sayings pertaining to the subject. By comparing with contemporary preventive medicine principles, this study aims to present the most salient preventive measures found in the teachings of Prophet Muhammad and which can be useful in preventing COVID-19 epidemic. In addition, it follows the analytical approach in studying the subjects which could be related to the protection against infection transmission and compare them with well-established principles of preventive medicine. And the study follows a deductive approach to identify the most important rules and instructions pertaining to the subject from the Prophetic Sayings. The study found that the most preventive principles found in the Prophetic sayings are daily hand washing while massaging them, ensuring the cleanliness of the mouth and nose, encouraging the use of available means such as handkerchiefs to prevent the spread of coughing and sneezin