Summary: A descriptive study evaluated ChatGPT's output on COVID-19 vaccine conspiracy beliefs and compulsory vaccination. ChatGPT responses debunked conspiracies about SARS-CoV-2 origins and COVID-19 vaccines, supporting compulsory vaccination citing benefits like public health protection. However, it highlighted drawbacks such as ethical concerns and logistical challenges. While ChatGPT can challenge misinformation, it should not replace reliable sources like the WHO and CDC. Its use can offer clear, concise, and unbiased information, aiding in combating vaccine hesitancy and providing insights on compulsory vaccination.