The study aims to determine the effect of e-commerce on the profitability of commercial companies of Jordan’s economy and to study the magnitude of the effect of e-commerce (whether positive or negative). The research population includes the commercial companies that are listed on the Amman Financial Market for four years (2015-2018), which consisted of (10) Companies that meet the conditions. The results of the study show that e-commerce practices positively affected the profitability in the commercial companies, also e-commerce benefits on Return on Assets (ROA) and Return on Equity (ROE) for commercial companies in Jordan. The findings of this study indicate that there is an effect of e-commerce benefits on (ROA) for commercial companies, where (0.016). Findings also indicates that there is an effect of e-commerce benefits on ROE for commercial companies, where (0.012). The researcher suggests developing and improving electronic commerce operations in Jordanian companies t