Recently, several software’s, tools and various algorithms have been proposed by the researchers for developing effective medical decision support systems. Moreover, new algorithms and new tools are continued to develop and represent day by day. Diagnosing of heart disease is one of the important issue and many researchers investigated to develop intelligent medical decision support systems to improve the ability of the physicians. Neural network is widely used tool for predicting heart disease diagnosis. In this research paper, a heart disease prediction system is developed using neural network. The proposed system used 13 medical attributes for heart disease predictions. The experiments conducted in this work have shown the good performance of the proposed algorithm compared to similar approaches of the state of the art.